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System improves GC-MS performance


Laboratories performing food safety and authenticity, pharmaceutical, metabolomic, anti-doping and other analyses using gas chromatography-mass spectrometry (GC-MS) will now be able to achieve higher levels of performance using high-resolution accurate-mass (HRAM) Orbitrap mass spectrometry.

The Q Exactive GC hybrid quadrupole-Orbitrap GC-MS/MS instrument combines gas chromatography and high-resolution accurate-mass (HRAM) Orbitrap mass spectrometry. The easy-to-use system is designed to provide comprehensive characterization of samples in a single analysis and increased performance in compound discovery, identification and quantitation.

Manufacturer says that in laboratory tests, the new system has shown quantitative capability equivalent to high-performing GC-MS triple quadrupole systems, especially when comparing analytical parameters such as sensitivity, precision and linearity. The technology is designed to advance chemical analyses within laboratories limited by currently available full scan GC-MS technologies, such as time-of-flight (TOF) and quadrupole-time-of-flight (Q-TOF) mass spectrometry , or comparable technologies. The system is suitable for untargeted profiling experiments and can add new capabilities to screening in food safety, forensic toxicology and anti-doping. Thermo Fisher Scientific


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