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$42M supports multidisciplinary study of aging across Canada


Halifax, NS – A major study that will provide in-depth understanding of aging has received a shot in the arm. The Canadian Longitudinal Study on Aging (CLSA) has been awarded a $41.6 million grant from the Canadian Institutes of Health Research (CIHR) to continue its work for the next five years.

The most comprehensive study of aging ever undertaken in Canada began in 2010 and is led by researchers at Dalhousie, McMaster, and McGill universities. Dr. Susan Kirkland of Dalhousie Medical School’s Department of Community Health and Epidemiology is one of three principal investigators.

“This is a landmark study that will contribute to our understanding of the aging process,” she says. “It will provide information on the ways in which we can address health outcomes that matter to people — such as maintaining quality of life and independence — as well as contribute evidence that can be used to make improvements to the health-care system to meet the needs of this growing population.”

A total of 50,000 Canadians are being followed over 20 years. The CLSA collects information on the changing biological, medical, psychological, social, environmental, and economic aspects of people’s lives as they get older.

So far, hour-long telephone interviews have been completed with more than 21,000 individuals, aged 45 to 85, who were randomly selected from across Canada. An additional 26,000 people have taken part in extensive home-based interviews, and have visited one of the 11 data collection sites to undergo a range of physical tests. Hearing, heart function, bone density, mobility and many other measures related to overall health are being collected by the CLSA team. The final participants required to reach the 50,000 mark are now being recruited.

The CLSA has operations in several Canadian cities. Dalhousie hosts a data collection site and a computer-assisted telephone interviewing centre that interviews people across the country.

The National Coordinating Centre and the Biorepository and Bioanalysis Centre are based at McMaster University. The Statistical Analysis Centre is at McGill University, and the Genetics and Epigenetics Centre is located at the University of British Columbia.

A key feature of the CLSA is that its data is available to be used by researchers from many disciplines. Data from more than 21,000 participants who took part in telephone interviews are now available. Already, researchers have made requests for data to further research on topics such as caregiving, hearing loss, neurological conditions, injuries, and the health of older veterans.

The CLSA was launched through $50 million in grants. Funders include CIHR, the Canada Foundation for Innovation, provinces and universities — including the Nova Scotia Research and Innovation Trust and Dalhousie University — as well as other partners.

Reported by Allison Gerrard, Dalhousie University