Lab Canada

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Research Results

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Open-source molecule helps to further cancer research

September 8, 2015 by Lab Canada Toronto, ON – Researchers from the Ontario Institute for Cancer Research (OICR) and the Structural Genomics Consortium (SGC) at the MaRS Discovery District recently developed a new drug prototype called OICR-9429 and made it freely available to the research community.…
News CollaborationsLaboratoryLife SciencesResearch Results

Collaboration uses stem cell technology to further personalized medicine

September 8, 2015 by Lab Canada Toronto, ON – A collaborative team of clinician-scientists and stem cell biologists has developed a powerful new method to generate 3D bile duct structures from human stem cells in order to study and develop new personalized treatments for bile duct…
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Why we’re smarter than chickens

August 31, 2015 by Lab Canada Toronto, ON – Toronto researchers have discovered that a single molecular event in our cells could hold the key to how we evolved to become the smartest animal on the planet.   Benjamin Blencowe, a professor in the University of…
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Researchers develop microchip that predicts viability of donor lungs

August 31, 2015 by Lab Canada Toronto, ON – University of Toronto researchers have found a way to determine quickly if a donor lung is suitable for transplant by using a microchip to measure biomarkers. This innovation can eliminate the leading cause of post-operation death. Biomarker…
News LaboratoryLife SciencesResearch Results

New mouse embryo model furthers neurodegenerative disease research

August 19, 2015 by Lab Canada Montreal, QC – Scientists at the Montreal Neurological Institute and Hospital -The Neuro, at McGill University and the McGill University Health Centre, have made a breakthrough in understanding an important protein, called Netrin1, that brings cells together and maintains their…
News General Science & ResearchLaboratoryResearch Results

Microplastics entering ocean food web through zooplankton

August 19, 2015 by Lab Canada Vancouver, B.C. – Tiny microscopic animals called zooplankton are ingesting plastic particles at an alarming rate, according to a new study by Dr. Peter Ross, head of the Ocean Pollution Research Program at Vancouver Aquarium Marine Science Centre. That could…
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Nanotech chemo delivery system leaves healthy cells unharmed

August 19, 2015 by Lab Canada Halifax, NS – A researcher at Dalhousie Medical School has developed a new way to deliver chemotherapy drugs. Using nanotechnology, the novel system releases chemo in cancerous cells only, leaving healthy cells alone. The work was recently published in Nature’s…
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Trans fats, but not saturated fats, linked to greater risk of death

August 18, 2015 by Lab Canada Hamilton, ON – A study led by researchers at McMaster University has found that that trans fats are associated with greater risk of death and coronary heart disease, but saturated fats are not associated with an increased risk of death,…
News LaboratoryLife SciencesResearch Results

Mutation to single gene makes mice brainy

August 17, 2015 by Lab Canada Vancouver, BC – Scientists at the University of British Columbia (UBC) have created unusually intelligent mice by causing a mutation to a single gene. While the research is a long way from reaching human trials, it helps researchers identify a…
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Study uncovers the molecular mechanism leading to addiction in humans

August 11, 2015 by Lab Canada Montreal, QC – A new study opens the field to new understanding of the molecular mechanism underlying addiction in humans. The study was published on August 4 in the journal Molecular Psychiatry by the team led by Salah El Mestikawy,…
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Possible “obesity gene” discovered by Canadian researchers

August 11, 2015 by Lab Canada Vancouver, BC – Scientists at the University of British Columbia have discovered a gene that could be an important cause of obesity.   The gene, which encodes a protein called 14-3-3zeta, is found in every cell of the body. But…
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Study links high-fat feeding with impairments in critical brain pathway

July 28, 2015 by Lab Canada Montreal, QC – High-fat feeding can cause impairments in the functioning of the mesolimbic dopamine system, says Stephanie Fulton of the University of Montreal and the CHUM Research Centre (CRCHUM). This system is a critical brain pathway controlling motivation. Fulton’s…
News ChemistryLaboratoryResearch Results

Discovery opens door to greener preparation of iodide reagents

July 21, 2015 by Lab Canada Montreal, QC – Researchers at McGill University have discovered a clean photo-driven pathway for the efficient synthesis of aryl iodides under extremely mild conditions. The finding, published June 18 in the Journal of the American Chemical Society, provides a more…
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Canadian scientists discover how HIV escapes the body’s antiviral responses

July 15, 2015 by Lab Canada Montreal, QC – A Canadian research team at the IRCM in Montréal, led by molecular virologist Éric A. Cohen, PhD, have made a significant discovery on how HIV escapes the body’s antiviral responses. The team uncovered how an HIV viral…
News LaboratoryMaterials ScienceResearch Results

Physicists shatter stubborn mystery of how glass forms

July 10, 2015 by Lab Canada Waterloo, ON – A physicist at the University of Waterloo is among a team of scientists who have described how glasses form at the molecular level and provided a possible solution to a problem that has stumped scientists for decades.…
News LaboratoryMaterials ScienceResearch Results

Researchers map rules governing the structure of glass

July 10, 2015 by Lab Canada Saskatoon, SK – University of Saskatchewan materials scientists Min Wu and John Tse have solved a small piece of a puzzle that has perplexed researchers for years: the structure of glass, or more precisely, metallic glass. Metallic glasses are made…
News BiologyLaboratoryResearch Results

Rapid decline in bumblebee species caused by climate change, study finds

July 10, 2015 by Lab Canada Ottawa, ON – In the most comprehensive analysis of the impact of climate change on critical pollinators, researchers have found that rapid declines in bumblebee species across North America and Europe are strongly linked to climate change. The study was…
News BiologyLaboratoryResearch Results

Global trends show seabird populations dropped 70% since 1950s

July 9, 2015 by Lab Canada Vancouver, BC – University of British Columbia (UBC) research shows world’s monitored seabird populations have dropped 70 per cent since the 1950s, a stark indication that marine ecosystems are not doing well. Michelle Paleczny, a UBC master’s student and researcher…
News LaboratoryMaterials ScienceResearch Results

Study brings black phosphorus one step closer to being the next silicon

July 7, 2015 by Lab Canada Montreal, QC – As scientists continue to hunt for a material that will make it possible to pack more transistors on a chip, new research from McGill University and Université de Montréal adds to evidence that black phosphorus could emerge…
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Researchers develop quick, easy test to detect superbugs

July 7, 2015 by Lab Canada Hamilton, ON – Infectious diseases such as hepatitis C and some of the world’s deadliest superbugs – C. difficile and MRSA among them – could soon be detected much earlier by a new diagnostic test, designed to identify dangerous pathogens…
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Research on gonorrhea uncovers new immune system trigger

June 24, 2015 by Lab Canada Toronto, ON – Researchers at the University of Toronto have uncovered how Gram-negative bacteria – a broad class of bugs that cause diseases ranging from gonorrhea to diarrhea and pneumonia – can trigger an immune system reaction. The discovery could…
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Scientists record locations of all proteins in a cell

June 22, 2015 by Lab Canada Toronto, ON – Scientists at the University of Toronto have recorded, in what they say is unprecedented detail, the locations of all proteins in a cell. This new protein map allows scientists to look much more closely into what happens…
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Researchers target host rather than the flu virus

June 16, 2015 by Lab Canada Toronto, ON – The flu kills hundreds of thousands of people around the world every year, yet there is essentially only one class of drugs to fight the ever-changing virus. Cases of flu resistant to this class of drugs have…
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Full E.coli genome sequenced on smartphone-sized device

June 15, 2015 by Lab Canada Toronto, ON – Researchers in Canada and the U.K. have for the first time sequenced and assembled de novo the full genome of a living organism, the bacteria Escherichia Coli, using Oxford Nanopore’s MinIONTMdevice, a genome sequencer that can fit…
News BiologyLaboratoryResearch Results

Mercury buildup in birds sounds warning for all

May 15, 2015 by Lab Canada London, ON – Higher-than-normal mercury levels may be wiping out the endangered arctic ivory gull, but now Western researchers are warning other species – including humans – are at risk from this deadly neurotoxin. Mercury levels in arctic ivory gulls…
News General Science & ResearchLaboratoryResearch Results

Discovery could pave way to new approaches to medical diagnostics

May 15, 2015 by Lab Canada Waterloo, ON – A researcher at the University of Waterloo has theoretically demonstrated that it is possible to detect a single nuclear spin at room temperature, which could pave the way for new approaches to medical diagnostics. Published in the…
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New mode of cardiovascular communication is uncovered

May 15, 2015 by Lab Canada Toronto, ON – Scientists at the University of Toronto have found that blood vessel cells have a deeper level of communication than previously believed. This discovery could lead to new diagnostics and more targeted treatment for cardiovascular disease, according to research…
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Study uncovers mechanism governing sarcoma metastasis

May 15, 2015 by Lab Canada Vancouver, BC – Research published this week by scientists at the BC Cancer Agency in Cancer Cell brings new hope for the treatment of high-risk childhood sarcomas – a type of cancer that has seen almost no treatment improvement in…
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Researchers take a closer look at how the Huntington’s gene works

May 15, 2015 by Lab Canada Vancouver, BC – Huntington’s disease is caused by a mutation in the Huntington’s disease gene, but it has long been a mystery why some people with the exact same mutation get the disease more severely and earlier than others. A…
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Researchers unlock ability to create human articular cartilage

May 13, 2015 by Lab Canada Toronto, ON – A team of scientists, led by Drs. Gordon Keller and April Craft from University Health Network’s McEwen Centre for Regenerative Medicine has been able to generate articular chondrocytes and cartilage tissue from human pluripotent stem cells in…
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Researchers identify cell-changing gene that can cause cancer

May 12, 2015 by Lab Canada Halifax, NS – There are eight known human herpes viruses, all capable of establishing life-long infection. The most recently discovered of these viruses, herpesvirus-8, is the cause of several AIDS-related cancers – including a form of skin cancer known as…
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New findings on the role of calcium channels in brain blood flow

May 5, 2015 by Lab Canada Calgary, AB – Researchers at the University of Calgary have identified how calcium channels in the cerebral arteries play an important role in controlling blood flow to the brain. Scientists performed the first human-based study to look at human cerebral…