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200 bar flow chemistry system enables solvent free reactions

A new application note describes the use of the R-series high-pressure pump module for running continuous flow reactions under solvent free (neat) conditions and pumping liquefied gases at pressures necessary for high reaction temperatures. These higher temperature and pressure conditions enable solvent-free uncatalysed amination of 2-chloropyridine with dimethylamine in high throughput (30 grams / hour).

The high-pressure pump allows the system to reach up to 200 bar, but has all the functionality of standard pump modules and can be added to an existing two-pump system for increased capability.




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