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Nanofleece material enhances clarification capabilities in liquid prefiltering

SartoguardNFprefilters feature combine high performance polyethersulfone (PES) membranes and innovative nanofleece technology. This is the first time that PES nanofleece material is being used for liquid prefiltration applications in biopharmaceutical manufacturing. The newly developed nanofleece technology provides an ultrafine fleece structure based on a small nanofibre diameter of 120-150 nm compared with the fibre diameter of conventional fleece materials of >500 nm. The resulting fleece structure offers enhanced clarification capabilities, even for extremely fine contaminants, along with a high-dirt holding capacity, fast flow rates and high total throughput performance.


The prefilters provide downstream protection of more expensive sterilizing-grade and Mycoplasma-retentive filters in challenging prefiltration applications for biopharmaceutical manufacturing. In combination with high total throughput performance, the prefilters offer significant cost-saving potential due to their ultrafine retention performance, which ensures removal even of extremely small particulate-based contaminants.


Sartorius Stedim Biotech




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