Available with HumSilencer noise-cancelling technology, the Digidata 1550A Low-Noise Data Acquisition System provides analog-to-digital conversion of biological signals measured in electrophysiology experiments. The built-in adaptive noise cancellation technology provides single-click elimination of the 50 and 60 Hz line-frequency noise that can severely impair analysis of biological signals.
The dysfunction of ion channels, which regulate the flow of ions in and out of cells, is implicated in numerous neurological and cardiovascular diseases. Measuring ionic current through the channels requires a patch clamp system sensitive enough to record a small signal—on the order of pico to nano amps (10-12 to10-9 A)—and that is not susceptible to electrical noise in the laboratory environment. Improperly shielded or grounded electrical devices and wiring can inadvertently contribute a 50 or 60 Hz “hum” or background line-frequency noise that overpowers the ion channel signal and requires significant time to troubleshoot.
The digitizer rapidly identifies local line-frequency noise and suppresses extraneous noise amplitude up to 20V peak to peak at the analog input in less than one second. Molecular Devices
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