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Fluorescence and brightfield analysis combined in a single platform

High-performance image analysis system is designed for discovery research. Combining fluorescence and brightfield analysis capabilities in a single platform, with precision cell modelling, the system is suitable for IHC biomarker quantification.

A major challenge in research today is retrieval of quantitative, reproducible data from tissue-based IHC studies. The system provides expert tools for researchers to extract the most from their studies. Powerful colour separation and multi-marker colocalization functionality provides advanced insight and unbiased measurement of multiple antigen immunostaining in brightfield or fluorescent samples. Sophisticated cell modelling accurately detects and quantifies differential expression of staining in cellular compartments, providing detailed insight into cytoplasmic, membrane and nuclear biomarker localization.

Advanced dual staining capabilities enable researchers to identify cell cohorts at the molecular level. Use one marker to identify a population of interest and then quantify expression of a second, providing exceptional analysis performance and greater understanding of a user’s slides. Algorithms are easily adjusted and optimized for different markers, tissue and protocols giving a flexible platform for drug discovery applications.

Leica Microsystems


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